In amyotrophic lateral sclerosis NIACINAMIDE (ALS) spinal motor neurons (SpMN) progressively degenerate while a subset of cranial motor neurons (CrMN) are spared until late stages of the disease.Using a rapid and efficient protocol to differentiate mouse embryonic stem cells (ESC) to SpMNs and CrMNs, we now report that ESC-derived CrMNs accumulate
Conservation Agriculture (CA) is promoted by research and development (R&D) agencies to sustainably intensify agricultural systems with the goals of improving food security and livelihoods and adapting food systems to global climate change.Despite the many benefits of CA, there are few farmers around the world that have simultaneously implemented a
Pyoderma gangrenosum (PG) is a rare autoinflammatory skin disease characterized by recurrent ulcers.It is a diagnosis of exclusion and treatment can be challenging due to limited evidence-based therapies.While surgical management is typically avoided due Hoses to the risk of pathergy, it can be warranted in specific cases.Here, we have illustrated
The human experience of art is unique, being associated with exceptional and transcendent states of consciousness.These experiences are formed based on the interaction between the PLAYTIME work of art itself, the observer, and the context.Using the multilevel modelling with crossed random effects analysis, we explored the connection between the aff
The current Dutch colonial Kitab Undang-Undang Hukum Pidana (KUHP) needs to be replaced with an updated Indonesian Criminal Code.Legal scholars, especially those specializing in criminal law, have long debated the overhaul, reformulation, modification, and even reformation of the Criminal Code to conform to the guiding principles of the Indonesian